Risk Factors of Hypertension

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Across
  1. 3. Syndrome featuring obesity, HTN, and dyslipidemia
  2. 4. Obstructive _____ apnea is a secondary cause of HTN
  3. 5. Polygenic risk loci (e.g., AGT, ACE) influence this
  4. 8. Phenochromocytoma secretes excess _____ and norepinephrine
  5. 9. Autoantibodies against this receptor worsen resistant hypertension
  6. 11. Vasoconstrictor peptide derived from endothelium
  7. 12. NSAID-induced HTN via inhibition of _____ synthesis
  8. 14. Endothelial dysfunction marker associated with hypertension
Down
  1. 1. Excessive aldosterone secretion independent of renin
  2. 2. Genetic disorder causing early-onset HTN via salt retention
  3. 4. Excessive _____ activity in stress-induced HTN
  4. 6. Mineralocorticoid excess due to 11β-HSD2 deficiency
  5. 7. Hormone from adipose tissue contributing to insulin resistance & HTN
  6. 10. Chronic kidney disease leads to impaired excretion of this ion, raising BP
  7. 13. Excessive activation of this system (RAAS) leads to vasoconstriction & sodium retention