Across
- 2. City in western Colorado where US Route 6 intersects with Interstate 70.
- 4. Nevada city where US Route 6 intersects with Interstate 80.
- 8. State where US Route 6 begins.
- 9. Pennsylvania city located along US Route 6.
- 10. New York town located along US Route 6 in the Hudson Valley.
- 13. State where US Route 6 crosses the Rocky Mountains.
- 14. Illinois city through which US Route 6 passes on its way towards Chicago.
- 17. Massachusetts town where US Route 6 intersects with State Route 39.
- 19. Scenic peninsula and popular tourist destination in Massachusetts with which US Route 6 is associated.
- 20. County in California known for its wine production, located along US Route 6.
Down
- 1. Connecticut town where US Route 6 intersects with US Route 72.
- 3. Ohio city through which US Route 6 passes.
- 5. New York town known as the birthplace of the women's rights movement, located along US Route 6.
- 6. Massachusetts town where US Route 6 ends.
- 7. Bridge that US Route 6 crosses over Nantucket Sound.
- 11. Desert that US Route 6 passes through in California.
- 12. Large freshwater lake that US Route 6 parallels for a stretch in Pennsylvania.
- 15. Indiana town located along US Route 6 in the northern part of the state.
- 16. Connecticut city where US Route 6 intersects with Interstate 84.
- 18. County in Nevada that US Route 6 traverses on its way towards Utah.
