Across
- 1. This T cell type assists other white blood cells in immunologic processes. CD4+. Has type 1 and type 2.
- 4. This T cell kills target cells directly. CD8+
- 8. full word for a substance that induces an immune response.Recognized by Ab, BCR, Peptide on MHC
- 10. a type of APC that presents antigen in the context of MHC to T cells
- 11. a type of white blood cell responsible for producing antibodies when it differentiates into a plasma cell. Can be naive, plasma cell, or memory cell.
- 13. The part of an antibody that BINDS to the antigen.
- 14. A large white blood cell that ingests foreign particles and infectious microorganisms.
- 19. T cell type that suppresses/limits immune responses. CD4
- 21. protein family to which antibodies and B-cell receptors belong. Different types related to different immune functions. Ex. IgE -allergies
- 24. full word for a molecule found in the outer membrane of gram-negative bacteria. This can bind TLR-4 on macrophages and dendritic cells
Down
- 1. Combination therapy for HIV that includes three antiretroviral medications. These medications are consistently altered based on the status of the patient and the different variances in the populations of HIV cells, one of the fastest evolving things on the planet.
- 2. abbreviation for cells that present antigens to T cells to initiate an immune response. Ex. dendritic cells
- 3. full word for the general designation of many of the different cytokines, chemical messengers secreted by immune cells that help in their communication with other cells
- 5. a type of lymphocyte that plays a central role in cell-mediated immunity.Can be helper, regulatory, or cytotoxic.
- 6. full word for the family name for cytokines that help cells to resist viral infections; type 1 interferons include IFN-alpha and IFN-beta, as distinguished from IFN-gamma.
- 7. full word for a protein produced by the adaptive immune system that recognizes and binds to specific foreign substances. Highly variable. Lock and key type binding.
- 9. abbreviation for the type of immune cell involved in the destruction of virus-infected cells and tumor cells.Innate immunity.
- 12. A surface protein on certain T cells, often associated with helper T cells. (TH and Treg)
- 15. A surface protein on certain T cells, often associated with cytotoxic T cells.(TC)
- 16. Member of TNF receptor family expressed on certain cells that makes them susceptible to being killed by cells expressing the Fas ligand
- 17. general term for proteins that recognize molecular patterns on pathogens
- 18. Molecular patterns found on pathogens and recognized by the innate immune system.
- 20. A transcription factor associated with regulatory T cells.
- 22. Motifs found in cytoplasmic tails of immune receptors. involved in signal transduction
- 23. Abbreviation for a complex that presents peptides from inside the cell to T cells. Class I and II.