SDL 23

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Across
  1. 3. cause of ARDS due to receiving supplemental O2 which causes radicalization of oxygen then sloughing off of endothelial cells and Type I pneumocytes
  2. 5. medication given to the mother before delivery to help mature the fetal lung tissue
  3. 8. complication of prematurity that is characterized by bowel wall necrosis
  4. 9. cause of ARDS characterized by intense inflammatory response to pathogenic infiltration
  5. 12. a substance that reduces surface tension in the alveoli, deficient in NRDS, produced by type II pneumocytes
  6. 14. cause of ARDS with anti-leukocyte antibodies that initiate alveolar capillary damage within hours of exposure
  7. 16. major complication of NRDS, due to poor regulation of cerebral blood flow and rupture of germinal matrix vessels
  8. 17. repair of lung tissue following ARDS that suggests extensive lung fibrosis, results in a cystic appearance seen on CT and grossly
  9. 18. cause of ARDS from a state of prolonged hypotension and multiorgan failure
Down
  1. 1. cause of ARDS associated with circulation of blood by extracorporeal devices and major heart surgery
  2. 2. official term for alveolar collapse, results in perfused but not ventilated alveoli
  3. 4. membrane formed by pathologic accumulation of fibrin and cell debris that limits gas exchange. Found in both NRDS and ARDS
  4. 6. cause of ARDS- very feared complication of anesthesia, destruction of Type I and II cells, rapid degeneration within 4 hours after event
  5. 7. potentially blinding complication of prematurity, due to supplemental oxygen given in NRDS and subsequent rebound of VEGF
  6. 10. pathological basis of adult respiratory distress syndrome, results in hyaline membrane disease
  7. 11. normal adaptation that is impaired in ARDS, results in large intrapulmonary shunts through nonperfused regions of the lung
  8. 13. chronic lung disease in premature infants treated with mechanical ventilation, alveoli are enlarged with inflammatory cells and fibrosis
  9. 15. cause of ARDS associated with bone fracture, leads to chemical vasculitis