Across
- 3. Location for testing new therapies
- 4. Control used to simulate treatment
- 6. Common unit in dose measurement
- 9. Type of trial where treatment is concealed
- 12. Trial halted before completion: ___ stop
- 13. Primary doctor overseeing a trial (abbr.)
- 15. IRB stands for Institutional ___ Board
- 16. Investigator’s Brochure (abbr.)
- 17. Long-term study: follow-___
- 18. Subject group not receiving treatment
- 20. Acronym for Randomized Controlled Trial (abbr.)
- 21. Type of clinical trial that tests a treatment
- 23. Phase ___ – first stage of human testing
- 25. ___-label – all treatment details visible
- 26. ___ review – assessment by peers
- 27. Consent must be given ___ (freely)
- 29. Participants are often called ___
- 30. U.S. database of registered trials
- 33. Adverse ___ – undesirable effect
- 34. Organization that regulates drugs (abbr.)
- 35. Clinical research ___ (supports investigators)
Down
- 1. a request for authorization from FDA to administer an investigational drug or biological product to humans
- 2. Study conducted without bias (2 words)
- 4. Favorable outcome or improvement seen in response to treatment
- 5. Predefined outcome used to assess a treatment
- 7. Ideal trial design: randomized, double-blind, placebo-controlled (2 words, no space)
- 8. Type of assignment that removes bias
- 10. ___ – pioneer of clinical trials
- 11. Small group selected to represent a larger population
- 13. Study of how the body processes drugs
- 14. Pre-trial testing phase (animal/in vitro)
- 19. A group or treatment pathway in a clinical trial
- 22. Essential code for ethical research (1947)
- 24. Informed ___ (ethical requirement)
- 28. Common reference point in clinical comparisons
- 31. Form used for data entry (abbr.)
- 32. Documented test procedures (abbr.)