Across
- 3. Control used to simulate treatment
- 8. ___ review – assessment by peers
- 10. Primary doctor overseeing a trial (abbr.)
- 11. Essential code for ethical research (1947)
- 13. Documented test procedures (abbr.)
- 14. Informed ___ (ethical requirement)
- 15. Location for testing new therapies
- 17. Common reference point in clinical comparisons
- 18. Predefined outcome used to assess a treatment
- 19. Type of trial where treatment is concealed
- 22. Study conducted without bias
- 27. U.S. database of registered trials
- 29. Consent must be given ___ (freely)
- 30. Common unit in dose measurement
- 33. Type of clinical trial that tests a treatment
- 34. A request for authorization from FDA to administer an investigational drug or biological product to humans
- 35. Acronym for Randomized Controlled Trial (abbr.)
- 36. Organization that regulates drugs (abbr.)
Down
- 1. Phase ___ – first stage of human testing
- 2. Long-term study: follow-___
- 4. Subject group not receiving treatment
- 5. ___-label – all treatment details visible
- 6. James ___ – pioneer of clinical trials
- 7. A group or treatment pathway in a clinical trial
- 9. Type of assignment that removes bias
- 12. Adverse ___ – undesirable effect
- 15. Form used for data entry (abbr.)
- 16. Clinical research ___ (supports investigators)
- 20. Study of how the body processes drugs
- 21. Investigator’s Brochure (abbr.)
- 23. Trial halted before completion: ___ stop
- 24. Ideal trial design: randomized, double-blind, placebo-controlled
- 25. Participants are often called ___
- 26. Pre-trial testing phase (animal/in vitro)
- 28. Small group selected to represent a larger population
- 31. Favorable outcome or improvement seen in response to treatment
- 32. IRB stands for Institutional ___ Board