Specific Immune Response

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Across
  1. 2. Cause pathogens to clump together
  2. 3. Treated by insulin injections, pancreas transplant and immunosuppressant drugs
  3. 5. Immune system stops recognising 'self cells' and starts attacking healthy body tissue
  4. 8. Y-shaped glycoproteins called immunoglobulins
  5. 9. Body responds to antigens found outside the cells
  6. 11. Activated B cell divides by mitosis to give plasma cells and B memory cells
  7. 13. Type of cytokine produced by T-Helper Cells
  8. 14. B cells develop into B memory cells in case the same pathogen enters the body again
  9. 15. Affects skin and joints, can attack any organ
  10. 16. Type of B lymphocyte that forms plasma cell clones
  11. 17. T lymphocytes respond to cells of the organism that have been changed in some way e.g. early cancers and viral infections
  12. 18. Affects joints, no cure
  13. 19. Type of B lymphocyte that provides immunological memory
Down
  1. 1. Activated T-helper cells bind to the B cell APC
  2. 4. Can take days or weeks to become fully effective against a particular pathogen
  3. 6. Engulf and digest pathogens in phagocytosis
  4. 7. Type of B lymphocyte that produces antibodies for a particular antigen
  5. 10. Kills pathogens by making a hole in the membrane - produced by T-Killer Cells
  6. 12. Bind to toxins produced by pathogens
  7. 15. Mechanism where antibodies bind to complementary antigens