Spectroscopic structure and method validation

Edit Answers
12345678910111213141516171819202122232425262728293031323334353637383940
Across
  1. 3. Which mass analyzer traps ions using RF fields and helium gas?
  2. 4. Which parameter measures resistance to small method changes?
  3. 6. Which NMR component provides the external magnetic field?
  4. 9. Which validation parameter measures closeness to the true value?
  5. 11. Which mass analyzer uses radiofrequency electric fields?
  6. 12. What important pharmaceutical goal is ensured by method validation?
  7. 17. What process occurs when excited nuclei return to lower energy state?
  8. 18. Which validation parameter measures reproducibility of results?
  9. 21. Which hard ionization method uses high energy electrons?
  10. 22. What unwanted substances in drugs can be identified using MS?
  11. 24. Which parameter refers to the highest and lowest analyte concentration?
  12. 25. What process proves an analytical method is suitable for use?
  13. 28. Which mass spectrometry technique provides extremely high mass accuracy?
  14. 31. What HPLCMS output shows retention time versus intensity?
  15. 32. Which spectroscopy technique studies nuclei in a magnetic field?
  16. 33. Which parameter measures analyte detection without interference?
  17. 35. Which organization provides guidelines for analytical method validation?
  18. 37. What property allows nuclei to behave like tiny magnets in NMR?
  19. 38. What parameter identifies compounds during HPLC separation?
  20. 39. Which property allows detection of trace drug impurities?
  21. 40. Which ion separation method is based on ion travel time?
Down
  1. 1. Which NMR technique uses Fourier transformation?
  2. 2. What MS output provides molecular weight information?
  3. 5. What type of radiation excites nuclei in NMR?
  4. 7. Which soft ionization technique is widely used with HPLC?
  5. 8. Which feature measures the ability to separate ions accurately?
  6. 10. Which parameter evaluates proportionality to concentration?
  7. 13. Which analytical technique combines gas chromatography and mass spectrometry?
  8. 14. What term refers to the substance being measured in analysis?
  9. 15. Which hyphenated technique combines liquid chromatography with mass spectrometry?
  10. 16. Which ionization method is suitable for less polar drug compounds?
  11. 19. Which type of precision uses the same analyst and equipment?
  12. 20. What effect causes proton signals to move downfield?
  13. 23. Which nucleus is most commonly analyzed in NMR spectroscopy?
  14. 26. What π electron effect influences nearby nuclei in NMR?
  15. 27. What large compounds are commonly analyzed using MALDI?
  16. 29. What term refers to the position of an NMR signal on the delta scale?
  17. 30. Which NMR technique distinguishes enantiomers in mixtures?
  18. 34. Which ionization method uses a laser and matrix for ion production?
  19. 36. What process converts molecules into charged particles in MS?