Structure of an Antibody drug conjugate

Edit Answers
12345678910111213
Across
  1. 3. The type of cells that ADCs are designed to target (6 letters)
  2. 5. The process of attaching the drug to the antibody in an ADC (11 letters)
  3. 8. The type of diseases that ADCs are often used to treat (6 letters)
  4. 10. A technology used to produce monoclonal antibodies for use in ADCs, created by fusing an antibody-producing B cell with a myeloma cell
  5. 11. This part of the ADC binds to the target cell (8 letters)
  6. 12. The term for a substance used in an assay to detect the presence of the ADC in a sample (7 letters)
  7. 13. A type of linker that is stable in the bloodstream but releases the drug once inside the target cell (8 letters)
Down
  1. 1. A type of assay used to detect the presence of specific antibodies in a sample (11 letters)
  2. 2. The term for the ability of the ADC to bind specifically to its target cells and not to other cells (10 letters)
  3. 4. The component of an ADC that connects the antibody to the drug (6 letters)
  4. 5. The type of molecules often used as payloads in ADCs due to their ability to interfere with cell division (9 letters)
  5. 6. The region of the antibody that binds to the antigen
  6. 7. The term for the number of drug molecules attached to each antibody in an ADC (3 letters)
  7. 9. The type of bond often used to attach the drug to the antibody in an ADC (8 letters)