T cell and T cell receptor 3

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Across
  1. 6. The enzyme defect __________ leads to the accumulation of toxic purine nucleosides and nucleotides, resulting in the death of most developing lymphocytes within the thymus. It is a cause of severe combined immunodeficiency.
  2. 7. in adaptive immunity there are cells that aid in the response but do not directly mediate specific antigen recognition. They include phagocytes, mast cells, and NK cells.
  3. 8. The removal of antibodies specific for one antigen from an antiserum to render it specific for another antigen or antigens is called
  4. 9. any substance that enhances the immune response to an antigen with which it is mixed.
  5. 11. These are mucosal-associated lymphoid tissues located in the nasal cavity.
Down
  1. 1. this is is a rare genetic disorder characterized by the absence or severely reduced levels of mature B cells and immunoglobulins (antibodies) in the blood.
  2. 2. The acquired immune deficiency syndrome AIDS is a disease caused by infection with the human immunodeficiency virus (HIV-1). AIDS occurs when an infected patient has lost most of his or her ______ so that infections with opportunistic pathogens occur.
  3. 3. Immunization with antigen is called active immunization to distinguish it from the transfer of antibody to an unimmunized individual, which is called
  4. 4. _____is the response of antigen-specific lymphocytes to antigen, including the development of immunological memory
  5. 5. _____is a highly aggressive, undifferentiated form of lymphoid malignancy derived from a progenitor cell that is thought to be able to give rise to both T and B lineages of lymphoid cells. Most of these leukemias show partial differentiation toward the B-cell lineage (so called B-ALL) whereas a minority show features of T cells (T-ALL).
  6. 8. _____proteins are key linkers between receptors and downstream members of signaling pathways. These proteins are functionally heterogeneous, but all use a similar domain, known as an SH2 domain
  7. 10. _____immunity is immunity conferred on a naive or irradiated recipient by transfer of lymphoid cells from an actively immunized donor. This is called adoptive transfer