Across
- 2. An immunoglobulin intrinsic to the surface of B-cells that, when contacted by a specific homologous antigen, initiates B-cell proliferation (cloning)
- 3. The mature antibody of the humoral immune response, possessing the primary molecular structure described above.
- 5. A lymphokine derived from helper cells, predominantly responsible for T-cell proliferation, the generation of lymphokine activated killer (LAK) cells, and the activation of B-cells
- 8. Antigen-specific immunity mediated by B- and plasma-cell production of circulating or secretory immunoglobulins.
- 9. An antibody that can sensitize mast cells and basophils during allergic reactions, causing them to release histamine and other inflammatory mediators
- 11. Exaggerated immune response to a foreign allergen or antigen induced largely by the release of histamine and occurring within minutes.
- 13. Cytokine that interferes with the propagation of viruses and fills other immunological roles. INF-α is produced by phagocytic leukocytes, INF-β by fibroblasts, and INF-γ by lymphocytes.
Down
- 1. An allergic response to an allergen or antigen.
- 4. A cytokine secreted by a lymphocyte.
- 5. High protective resistance to a disease threat that is produced by the immune system or by some other nonspecific protective mechanism.
- 6. An enzyme present in tears and body secretions and fluids that helps in the destruction of bacterial cell walls.
- 7. A small amine compound, C5H9N3, released by mast cells during allergic reactions, which causes dilation of blood vessels, bronchoconstriction, itching, and other symptoms.
- 10. Any substance (or molecule) capable of inducing a specific immune response. Antigens include a wide variety of plant and microorganism components or toxins.
- 12. A proinflammatory cytokine with scores of reported activities, including the generation of fever, skeletal muscle proteolysis, and metabolic wasting. IL-1 also enhances the proliferation of T-helper and B-cells.