Test1

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Across
  1. 2. [A] Two factors that determine how much a neuron contributes to the LFP are _____A_____ of firing and _____B_____ of the neural architecture.
  2. 4. In Alzheimer's disease, BOLD-based biomarkers may fail because of impaired __________ __________.
  3. 11. The 3Rs of ethical animal research are __________, __________, and __________.
  4. 13. [B]The main positive BOLD signal is caused by a A of deoxyhemoglobin due to increased B.
  5. 14. [B] The three phases of the BOLD fMRI signal are the (A), the (B) BOLD signal, and the (C).
  6. 16. The __________ degeneration hypothesis proposes that vascular dysfunction occurs early in Alzheimer’s, before plaque or tau pathology.
  7. 18. [B] Two-photon microscopy is preferred over confocal because it allows _____A_____ imaging with less _____B_____.
  8. 19. The BOLD signal correlates most strongly with __________, not spiking output like MUA.
Down
  1. 1. [C] The three phases of the BOLD fMRI signal are the (A), the (B) BOLD signal, and the (C).
  2. 3. [A] Two-photon microscopy is preferred over confocal because it allows _____A_____ imaging with less _____B_____.
  3. 5. The 3Rs of ethical animal research are __________, __________, and __________.
  4. 6. [C] The three key haemodynamic changes in response to neural activity are increased _____A_____, _____B_____, and changes in _____C_____.
  5. 7. [B] The three key haemodynamic changes in response to neural activity are increased _____A_____, _____B_____, and changes in _____C_____.
  6. 8. [B] Two factors that determine how much a neuron contributes to the LFP are _____A_____ of firing and _____B_____ of the neural architecture.
  7. 9. [A] The three phases of the BOLD fMRI signal are the (A), the (B) BOLD signal, and the (C).
  8. 10. The 3Rs of ethical animal research are __________, __________, and __________.
  9. 12. [A] The three key haemodynamic changes in response to neural activity are increased _____A_____, _____B_____, and changes in _____C_____.
  10. 15. [A] The main positive BOLD signal is caused by a A of deoxyhemoglobin due to increased B.
  11. 17. GCaMP fluoresces when it binds to __________, allowing researchers to visualise changes in intracellular activity.