The Best Drug Delivery Form

3. The process by which a drug reservoir can be made by continuously dosing and sealing.
5. The transdermal delivery type in which a drug is dispersed in a matrix between back and adhesive layers.
6. The brand name for transdermal buprenorphine.
7. An estradiol transdermal spray that had unintended exposure to children and animals.
9. High voltage pulse applied to skin to form pores to increase permeability.
10. One of the ideal places for placement of a TDDS.
13. The layer that maintains contact with skin after application; pressure-sensitive.
14. Testosterone, estrogens, and progesterone are this type of therapy.
15. TDDS is this drug route, allowing to bypass first-pass metabolism.

1. Physiological major factor and rate-limiting factor in the drug absorption process.
2. The impermeable membrane of a patch that blocks the drug from the system and moisture from the skin.
4. TDDS is also preferred because of _____ drug release around the clock.
8. Inversely proportional to molecular weight.
11. One of the top reasons why TDDS may be preferred; stick it and forget it.
12. Tiny drug coated projections or needles used to pierce top layer of skin.