Across
- 1. Once one half, now only one
- 5. Combine with Guppy's Paw for infinite health
- 7. Only sin with three variations
- 8. Dislikes smoke
- 10. Only enemy to create orange creep
- 12. One of each heart type
- 13. Polyphemus, Soy milk, and Epic Fetus are...
- 14. Resistance
- 16. Only champion color without a drop
- 18. Boss that gives a random devil item
- 19. Most health gained from one item
- 21. Daddy Longlegs's alt
- 22. Red poop, but sometimes hearts
- 26. First item you get from donating
- 28. Item drop from super Envy
- 30. There are 176 of these
- 31. Lowest boss health, back in vanilla
Down
- 2. It will never leave you
- 3. HP + Tears + Shot speed down\
- 4. In the boss rush with Widow
- 6. Second time beating the Heart
- 8. Instant kills ANYTHING
- 9. New Afterbirth character
- 11. Was not a guppy item in vanilla, but is now
- 15. Wiggle, Whip, Ring, Pulse...
- 17. Item equivalent of 5 dice room
- 20. Unlocked upon beating the Purist
- 23. Treasure, secret, or error
- 24. Once a trinket, now an item
- 25. Boss item that did nothing in vanilla\
- 27. Starts without red hearts, but can gain them
- 29. Bisnap's first rebirth episode title
- 30. Beat two floors without taking damage to unlock...
- 31. Mulliboom, Bomb, Mom...