Across
- 2. Comic-booky villain of Black Widow
- 3. Evil clone detective in the final season of Cloak and Dagger
- 8. Online cult in Falcon and the Winter Soldier
- 10. Doctor in the New Mutants
- 12. The human "villain" of the Inhumans who wanted the humans to be treated slightly better and not be slaves
- 16. Group of magic evil SECRET people in Ms. Marvel
- 18. Villain of first ever Spider-Man movie
- 20. Giant mech at the end of The Wolverine
- 21. The tech corporation formed in Iron Man 3
- 25. FBI agent who works for Fisk in final season of original Daredevil show
- 27. Computer that appeared as their comic book form in Captain America: The Winter Soldier
- 30. Ninja cult who the Defenders fight
- 35. Shang-Chi's father in his first movie
- 36. Only surviving family member of the Gnucchi family who swore vengeance on Castle in One Last Kill
- 37. Mayor and overall Daredevil: Born Again Season 2
- 38. Villain of She-Hulk and wife of Absorbing Man
- 39. Comic-booky character who was the villain of the Agents of S.H.I.E.L.D. pilot
- 41. Telepathic in the first season of Jessica Jones
- 43. Finish the quote from X3: "I'm the _____, B****
- 47. Villain who gave Wade Wilson his powers
- 49. Overall villain of Iron Heart
- 51. The armor that attacks Thor in his origin movie
- 54. Villain that brought together the Avengers
- 56. This alien who was played by Clark Gregg was referred to as the ____
- 60. Thor sequel villain who wanted "Darkness", I guess
- 62. Judgy villain in Moon Knight
- 65. Agent Carter Recurring villain
- 67. Murderer of Ben Parker in Spider-Man 3
- 68. Twist villain of the finale of Agents of S.H.I.E.L.D. Season 5
- 69. Final villain of Jessica Jones's comic name
- 73. Comic-booky villain of Spider-Man 4
- 76. Title villain of Fantastic Four sequel
- 78. This villain got a spinoff show where they fight the Kingpin of crime
- 79. X-Men: First Class Villain
- 82. Comic-booky female villain of Iron Fist Season 2
- 85. Hulk villain who wanted to take down the president in Captain America 4
- 86. Monster villain of Kraven the Hunter
- 87. Vampire villain of Morbious
- 88. Man Drax and Mantis were tasked to chase after in Holiday Special and also killed Magneto's parents
- 90. Jessica Jones's mom in Season 2 of her show
- 92. AI villain of Agents of S.H.I.E.L.D. Season 4
- 93. Comic-booky villain of Ant-Man and the Wasp
- 95. Assassin in Ben Affleck Daredevil movie
- 97. Villain of original 2000's Fantastic Four
- 98. The only villain who actually didn't know Peter Parker is Spider-Man in Spider-Man: No Way Home
- 100. First villain of the Amazing Spider-Man
- 101. Villain of first Venom movie
- 102. Teased villain of final Venom movie
- 103. Creator of H.Y.D.R.A. in Agents of S.H.I.E.L.D. Season 3
- 104. Villain of the best Spider-Man sequel
- 106. Villain of third Captain America movie
- 107. Billionaire in Iron Man 2
- 108. Company created by Tony Stark that chased after the Wonder Man
- 109. Relative of Elsa and villain of Werewolf by Night
- 110. Title villain of 90's X-Men Movie
Down
- 1. Villain of final Guardians of the Galaxy movie
- 2. Guy Who Created Robots in Days of Future Past
- 4. Final villain of Season 1 of Loki
- 5. T'Challa's cousin in his first movie
- 6. Successor of Ronan in the Marvels
- 7. Captain America: First Avenger villain
- 9. Comic booky villain of final Blade movie
- 11. General in Incredible Hulk
- 13. Wolverine's Brother in Origins
- 14. Villain in Europe in Spider-Man: Far From Home
- 15. Twist villain of WandaVision
- 17. Watery villain of the Black Panther sequel
- 19. Teased villain in Hawkeye
- 22. Name of the suit of the villain in Iron Man
- 23. Comic-booky villain in the pilot of Agents of S.H.I.E.L.D. Season 2
- 24. Mastermind ninja villain of first season of Iron Fist
- 25. Reoccuring villain Luke Cage Season 2
- 26. Fireball villain of Dr. Strange
- 28. Fantastic Four: First Steps Villain
- 29. Punisher Season 2 religious villain
- 31. Scientist who created Wolverine and returned in X2
- 32. Mutant leader of the Hand in Elektra
- 33. Daredevil's girlfriend and recurring villain of season 2 of his show
- 34. Original villain of the Multiverse Saga but only was in third Ant-Man movie
- 40. Computer in Captain Marvel
- 42. Villain of first MCU Spider-Man movie, he's not Batman, he's not Birdman, he's the ____
- 44. Peter Quill's father
- 45. God-Butcher in Thor 4
- 46. Thor's sister in his third movie
- 48. Sentry's second side that destroyed the city in the Thunderbolts
- 50. First villain of Blade
- 52. Twist villain of Eternals
- 53. Villain of the week of Into the Spider-Verse sequel
- 55. Scientist variant of Doc Ock in Spider-Man: Into the Spider-Verse
- 57. Super-Skrull in Secret Invasion
- 58. Final villain of the Avengers in the Infinity Saga
- 59. Cybernetic Wolverine in the movie Logan
- 61. Villain of Eyes of Wakanda pilot
- 63. Villain who appeared shortly in Daredevil: Born Again Season 1 whose love of art was so passionate, it's a crime
- 64. Twist villain in Doctor Strange sequel
- 66. Villain of Blade sequel
- 70. Title villain of 80's X-Men Movie
- 71. ADRd villain of Madame Web
- 72. Title villain of Venom sequel
- 74. Ex of Agatha and villain of her show
- 75. The kid the Agents of S.H.I.E.L.D. were sent back in time to protect in the final season of their show
- 77. Squidward [Iron Man nickname "Squidward" refers to which leader of the Black Order in Infinity War]
- 80. Kid in Deadpool sequel
- 81. First villain of the Guardians of the Galaxy
- 83. Peter's friend and the murderer of Gwen Stacy in Amazing Spider-Man sequel
- 84. Twin of Professor X and villain of Deadpool's third movie
- 87. Overall villain of the first X-Men
- 89. Variant of He Who Remains in season 2 of Loki
- 91. Name of crime boss in the first episode of Daredevil
- 94. Comic-booky villain of the first Ant-Man
- 96. Villain of the pilot of Luke Cage
- 99. Corporation that ruins Cloak and Dagger's life in first season
- 105. Title villain of Avengers sequel
- 107. Comic book name of the villain of Punisher Season 1