Toxidromes

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Across
  1. 5. The finding that helps distinguish opioid intoxication from opioid withdrawal
  2. 7. Classic medication exposure in an adolescent with anticholinergic delirium tachycardia mydriasis and dry mucous membranes
  3. 8. Intoxication syndrome marked by agitation hypertension tachycardia hyperthermia mydriasis and diaphoresis
  4. 9. Medication used for severe neuroleptic malignant syndrome also used in malignant hyperthermia
  5. 10. Disorder marked by fluctuating attention and awareness should be considered over primary psychosis in acute toxic presentations
  6. 13. Key physical examination finding that favors serotonin syndrome over sympathomimetic intoxication
  7. 15. Stimulant withdrawal feature that should prompt careful suicide risk assessment
  8. 16. First line treatment for ventricular dysrhythmia and hypotension due to tricyclic antidepressant overdose
  9. 17. Medication used to treat opioid withdrawal and opioid use disorder starting it too early can precipitate acute withdrawal
  10. 19. Cholinergic poisoning manifestation most responsible for early death
  11. 21. Medication that regenerates acetylcholinesterase in organophosphate poisoning
  12. 22. Toxidrome featuring CNS depression respiratory depression miosis and decreased bowel sounds
  13. 23. Immediate medication titrated until pulmonary secretions dry in organophosphate poisoning
  14. 24. Nutrient that should be administered in a patient with alcohol use disorder to prevent or treat Wernicke encephalopathy
  15. 25. Most common caffeine withdrawal symptom
  16. 27. First line treatment for alcohol withdrawal including prevention of withdrawal seizures and delirium tremens
  17. 29. Caffeine intoxication feature that may mimic generalized anxiety disorder or panic disorder
Down
  1. 1. Withdrawal syndrome that is uncomfortable but generally not life threatening features include diarrhea piloerection yawning and mydriasis
  2. 2. Alcohol withdrawal complication most likely 12–48 hours after cessation
  3. 3. Antidote for isolated anticholinergic delirium avoid if there is concern for tricyclic antidepressant overdose with QRS widening
  4. 4. Toxidrome with agitated delirium mydriasis dry skin urinary retention and decreased bowel sounds
  5. 6. Hyperthermic medication reaction with lead pipe rigidity and decreased reflexes following dopamine blockade
  6. 11. Life threatening alcohol withdrawal complication featuring delirium severe autonomic instability and hallucinations
  7. 12. ECG finding in tricyclic antidepressant overdose that should prompt sodium bicarbonate therapy
  8. 13. Toxidrome caused by organophosphate poisoning with salivation lacrimation diarrhea bronchorrhea and miosis
  9. 14. Dopamine agonist sometimes used in neuroleptic malignant syndrome
  10. 18. Withdrawal syndrome that can cause seizures hallucinations and delirium after abrupt cessation
  11. 20. Opioid overdose antidote used for respiratory depression
  12. 26. Serotonin syndrome treatment for moderate to severe symptoms after stopping serotonergic agents and providing supportive care
  13. 28. Medication used to relieve autonomic symptoms of opioid withdrawal such as hypertension tachycardia and diaphoresis