TRANSDERMAL DRUG DELIVERY

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Across
  1. 6. It is an enhancer that increases skin permeability by reversibly damaging the physicochemical nature of the stratum corneum to reduce its diffusional resistance
  2. 8. This agent is used as an enhancer for the mobility of large molecular weight drugs.
  3. 10. Type of TDDS that incorporate drug matrix layer between backing and frontal layers in which it is the polymer matrix that controls the release.
  4. 12. Polymeric drug-dispersed layer in monolithic TDDS.
  5. 13. A drug delivery of a charger chemical compound across the skin membrane using electrical field.
  6. 14. It is the term for the absorption wherein it is defined as the passage of drugs through the skin then into the bloodstream.
  7. 15. An example of type of TDDS patch that use as a treatment for angina.
Down
  1. 1. Type of TDDS that is indicated for ADHD in children.
  2. 2. It is a type of skin irritation that is one common disadvantage of TDDS which can occur at patch site.
  3. 3. One of the general considerations in transdermal usage that this substance should be avoided before applying patch as it can affect skin hydration and can alter partition coefficient between drug and skin.
  4. 4. This is the organ of the body in which it also the main site of TDDS action or application.
  5. 5. Example of a type of TDDS which is also known as the first TDDS to received FDA approval.
  6. 7. This is use to enhance transdermal drug delivery by the use of high-frequency ultrasound.
  7. 9. This layer must be pressure sensitive and has the ability to patch into the skin as well as it sometimes holds drug.
  8. 11. A category of controlled transdermal system that is designed to contain a drug reservoir usually in liquid or gel form.