TTS Metabolisme Xenobiotik Kelompok 6

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Across
  1. 6. How a toxin moves through the body: absorption, distribution, metabolism, and removal.
  2. 7. A reactive chemical intermediate that can trigger oxidative damage if not neutralized.
  3. 9. Measuring many small molecules in the body to detect exposure effects and detox changes.
  4. 11. Gradual buildup of a chemical in the body when intake is faster than removal.
  5. 12. An enzyme that adds a “glucuronic tag” to chemicals so they become easier to remove in urine or bile.
  6. 13. An enzyme that adds a sulfate tag to help the body eliminate a drug or toxin faster.
  7. 14. An enzyme that adds a methyl group, often reducing reactivity or altering detox speed.
Down
  1. 1. Too much bilirubin in the blood, often linked to problems in detox or bile flow.
  2. 2. A damaging chain reaction that attacks cell fats and membranes during oxidative stress.
  3. 3. An enzyme that attaches an acetyl group, changing how a chemical behaves and how quickly it is cleared.
  4. 4. A broad enzyme class that runs oxidation–reduction reactions during chemical breakdown.
  5. 5. A reaction that removes hydrogen atoms, reshaping a chemical so it can be processed further.
  6. 8. How a toxin harms the body by interacting with cells, proteins, and DNA.
  7. 10. The study of how gene differences make people respond differently to the same drug.