Type 2 Diabetes Review

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Across
  1. 2. What SGLT2 inhibitor requires a renal dosage adjustment for eGFR 20-29 and avoid use if <25
  2. 4. this class is responsible for inhibition of K+ ATP channels on the beta cell surface allowing insulin secretion
  3. 7. These are common counseling points of what type 2 diabetes oral medication: Take with food or milk in the morning. Use sunscreen and avoid sunlamps or tanning beds. Avoid alcohol due to a disulfiram like reaction. Report to HCP if NPO or reduced caloric intake.
  4. 9. this sulfonylurea does not require a renal dosage adjustment
  5. 10. What SGLT2 inhibitor requires a renal dosage adjustment for eGFR 20-59 and avoid use if <20
Down
  1. 1. this class modulates PPAR to promote insulin sensitivity through glucose-dependent glucose disposal and decreased hepatic glucose production.
  2. 3. this medication works by increasing glucose utilization by the muscle and decreasing hepatic gluconeogenesis, but does not stimulate insulin secretion
  3. 5. this enzyme is blocked preventing incretin hormones from being broken down promoting post-meal insulin secretion and decreasing glucagon.
  4. 6. The only DPP4 inhibitor that does not require a renal dosage adjustment is _____
  5. 8. promotes cellular uptake of glucose, amino acids, and fatty acids, and their conversion to glycogen,triglycerides, and protein