Across
- 3. The suffix of drugs within the SGLT-2 inhibitor drug family. These drugs work by increasing glucose excretion via the urine. Side effects of this drug family include glucosuria, UTIs, weight loss and rarely, diabetic ketoacidiosis.
- 5. A type of DPP-4 inhibitor. This drug works by inhibiting incretins, released by the GI tract.
- 6. A drug which is injected, and usually given as third line therapy in managing type 2 diabetes.
- 7. A biguanide which is considered “weight neutral”. It does not typically cause hypoglycaemia. It’s main side effects are GI tract upset and lactic acidosis.
Down
- 1. The most common sulfonylurea. These increase insulin production from the pancreas. This drug can cause weight gain and hypoglycaemia.
- 2. GLP-1 analogues mimic the action of this naturally occurring hormone. Examples of GLP-1 analogues are “exenatide” and “liraglutide”. Drugs which mimic this hormone are given as subcutaneous injections. Side effects of this family of drugs include weight loss, dizziness and rarely hypoglycaemia.
- 4. A type of thiazolidinedione. Its main side effects are weight gain, fluid retention and heart failure. This drug works by increasing sensitivity to insulin and decrease liver production of glucose. It does not cause hypoglycaemia.