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3. factors Soluble factors that stimulate pro-wound healing responses
7. an infectious agent that causes disease
8. Type of protein expressed by endothelial cells to enable weak leukocyte adhesion
9. C3a and C5a fragments that enhance inflammatory responses
12. A liquid with high surface tension
15. inflammatory cell that phagocytosis dead cells and debris within the wound bed
17. precursor to fibrin
19. Cell types that deposits collagen
23. The contractile fibroblast phenotype that is involved in granulation tissue remodelling
26. One of the four signs of inflammation (8 letters)
27. avascular, collage-rich tissue that is the end result of wound healing in adults
28. fourth phase of wound healing
30. Only verterbrates have this type of immunity

1. transendothelial migration
2. coagulation factor that activates thrombin
4. Humoral system comprised of 20 proteins that enhance inflammatory responses
5. process of forming new tissue
6. Soluble factors that stimulate pro-inflammation responses
10. C3b and C4b fragments facilitate this process
11. boundary between two phases
13. This tissue is the first line of host defense
14. First inflammatory leukocyte to accumulate within the wound
16. Leukocyte migration along a signaling gradient towards a site of inflammation
18. Surfaces with water contact angle above 65o are considered to be ______.
20. coagulation pathway that is initiated by biomaterials
21. Term that refers collectively to white blood cells
22. Initial step in leukocytes exiting the blood vessel
24. High-energy surfaces usually have ____ contact angle
25. first phase of wound healing
29. cell type that carries out angiogenesis