Viral structure

12345678910111213141516171819
Across
  1. 3. ___ means the binding interfaces between subunits is similar, but not identical at all interfaces
  2. 6. Term used to denote an infection viral particle.
  3. 10. ___ is a technique that takes many images of the same object from different angles to produce a 3D structure. This methods is useful for viral particles that do not form uniform shapes.
  4. 11. Viral structures that do not use simple helical or icosahedral symmetry are called __. These viruses typically have large viral genomes, enabling space to encode for unique strategies.
  5. 12. ___ EM enables scientists to visual virus particles budding from cells, but at relatively low resolution.
  6. 14. I am an enveloped virus with icosahedral symmetry. My glycoprotein interacts with the interior capsid proteins to maintain the symmetry.
  7. 17. Particles encased in a lipid bilayer are termed ____.
  8. 18. The term used to describe individual proteins that make up the protective shell surrounding the viral genome.
  9. 19. Most viruses are very small requiring an __ microscope to visual them.
Down
  1. 1. I am an enveloped virus and each viral particle looks slight different. Inside the envelope, there are eight segments that contain helical symmetry.
  2. 2. Some enveloped viruses are ___ meaning each particle looks somewhat different from the next.
  3. 4. ___ viral particles are hearty in various environments. They frequently can survive harsh stomach acids, drying out and detergents.
  4. 5. I am an icosahedral, naked viral particle with long fiber proteins projecting from the 12 penton vertexes.
  5. 7. Viruses with ___ symmetry surround the nucleic acid with protein, forming a “round” looking shell that protects the genome.
  6. 8. Term used to describe proteins that are made with potential energy and can change shape when triggered.
  7. 9. ____ uses proteins or viral particles frozen in vitreous ice and takes 1000s of images. Then particle picking and averaging reconstructs particles, producing 3D structures.
  8. 13. Enveloped virions must __ with a cellular membrane to deliver the viral genome within the cell.
  9. 15. Some viral vaccines use the self-assembly ability of viral capsids to produce ___ that look like virus, but lack genome and are therefore not infectious.
  10. 16. Viruses with ___ symmetry repeat a protein subunit many times to form a coil, coating and protecting the nucleic acid.