Viral structure

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Across
  1. 2. Viral structures that do not use simple helical or icosahedral symmetry are called __. These viruses typically have large viral genomes, enabling space to encode for unique strategies.
  2. 6. Some viral vaccines use the self-assembly ability of viral capsids to produce ___ that look like virus, but lack genome and are therefore not infectious.
  3. 7. ____ uses proteins or viral particles frozen in vitreous ice and takes 1000s of images. Then particle picking and averaging reconstructs particles, producing 3D structures.
  4. 8. Term used to denote an infection viral particle.
  5. 10. Viruses with ___ symmetry surround the nucleic acid with protein, forming a “round” looking shell that protects the genome.
  6. 12. Most viruses are very small requiring an __ microscope to visual them.
  7. 14. ___ viral particles are hearty in various environments. They frequently can survive harsh stomach acids, drying out and detergents.
  8. 16. ___ is a technique that takes many images of the same object from different angles to produce a 3D structure. This methods is useful for viral particles that do not form uniform shapes.
  9. 17. Term used to describe proteins that are made with potential energy and can change shape when triggered.
Down
  1. 1. I am an icosahedral, naked viral particle with long fiber proteins projecting from the 12 penton vertexes.
  2. 3. Some enveloped viruses are ___ meaning each particle looks somewhat different from the next.
  3. 4. ___ EM enables scientists to visual virus particles budding from cells, but at relatively low resolution.
  4. 5. Viruses with ___ symmetry repeat a protein subunit many times to form a coil, coating and protecting the nucleic acid.
  5. 7. The term used to describe individual proteins that make up the protective shell surrounding the viral genome.
  6. 9. I am an enveloped virus and each viral particle looks slightly different. Inside the envelope, there are eight segments that contain helical symmetry.
  7. 11. Enveloped virions must __ with a cellular membrane to deliver the viral genome within the cell.
  8. 13. Particles encased in a lipid bilayer are termed ____.
  9. 15. I am an enveloped virus with icosahedral symmetry. My glycoprotein interacts with the interior capsid proteins to maintain the symmetry.