Viral Vectors

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Across
  1. 3. RNA virus that integrates its DNA copy into the host genome
  2. 6. describes viruses designed to replicate in and kill cancer cells
  3. 10. describes newer adenovirus vectors with almost all viral genes removed
  4. 11. delivery vehicle used to carry therapeutic DNA into cells
  5. 12. circular DNA that remains in the nucleus but outside chromosomes
Down
  1. 1. small harmless virus that forms episomes and allows long-term gene expression
  2. 2. inherited liver disorder first targeted in early adenoviral gene therapy
  3. 4. cell genetic blood disorder now treated successfully with gene therapy
  4. 5. vivo type of therapy where gene delivery happens directly inside the body
  5. 7. disease for which adenoviral vector vaccines were widely used
  6. 8. body system that sometimes reacts to viral vectors
  7. 9. early viral vector used in gene therapy and vaccine development
  8. 12. vivo type of therapy where cells are modified outside the body and returned