Virology Basics Crossword

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Across
  1. 2. are created when virally-infected host cells fuse together to create giant multinucleated cells
  2. 5. the number of this Baltimore Classification are for single-stranded (negative-sense) RNA viruses
  3. 9. the cell receptor for Influenza virus
  4. 11. the name for the protein coat that must surround all viral genetic material
  5. 12. the shape of these viral coats means they must always be enveloped to be infection
  6. 15. the name for the individual protein components that makes the coat around viruses
  7. 16. the cellular compartment where the majority of DNA viruses replicate
  8. 18. the period during initial viral infection of a host cell where early enzymes and the genome are being made, where intracellular virus is present but no extracellular virus
  9. 19. this is always the first step in initiating infection
  10. 20. a laboratory diagnostic technique that can be used to detect the nucleocapsid antigen of Influenza virus in respiratory secretions
  11. 22. when a patient goes from antibody negative for a microbe to antibody positive for the same microbe
  12. 23. ________ transcriptase must occur before PCR in order to detect the presence of RNA viruses in clinical samples
  13. 25. the period where viral particles are being assembled but haven’t been released from the host cell yet
  14. 26. the majority of viral DNA viruses only contain 1 copy of their genetic material, which makes them __________
Down
  1. 1. the term for when the envelope and/or capsid degrades inside a host cell and releases the nucleic acid
  2. 3. the suffix for a viral family
  3. 4. the name of the spike that Influenza virus uses to bind to respiratory cells
  4. 6. the first immunoglobulin made in a new infection
  5. 7. the name of the spikes on enveloped viruses that are responsible for recognizing and binding to specific host receptors
  6. 8. the process by which most enveloped viruses are released from the host cell
  7. 10. _________ effect is the term for host cell changes in appearance due to some viral infections and can be diagnostic
  8. 13. the shape of these viral coast is very symmetrical and they can look like soccer balls
  9. 14. _____ sense RNA viruses have to create mRNA before it can be translated
  10. 17. some viruses have an RNA genome that consists of more than 1 linear piece. This is called a ____________ genome
  11. 21. how most icosahedral non-enveloped viruses leave the host cell
  12. 24. the protein that makes up this component of enveloped viruses is just under the surface of the envelope and helps with stability