Virus Genomes

2. While most dsDNA viruses replicate in the nucleus, my large genome enables me to encode everything I need to replicate in the cytoplasm.
6. ___ virus is a negative-sense RNA viral genome in the shape of a bullet.
9. I am an icosahedral, dsDNA virus. I replicate in the nucleus by first producing immediate early proteins.
10. Class 1 viruses all contain _____stranded, DNA genomes.
11. ____ is the process of producing mRNAs.
14. Negative-sense RNA viruses must package their ___ in order to produce mRNA and viral proteins.
17. ____, double-stranded RNA viruses replicate within their capsid shell to prevent activation of cytoplasmic innate sensors.
18. ____ genetic systems enable researchers to introduce mutations into viral genomes and recover the viruses.
20. I am a retrovirus that infects chickens, one of the first viruses associated with cancer.

1. I am a segmented dsRNA virus and cause GI symptoms.
3. The __ classification groups virus by how they produce mRNA.
4. Class IV viruses must first produce a ___ strand to their viral genome in order to produce more viral genomes.
5. Change in the viral genome which can be passed to the next generation.
7. I have a partially dsDNA circular genome that replicates in the nucleus.
8. I am a small, ss(+)RNA virus. I encode for a large polyprotein that is later cut into various viral proteins. A viral VPg is attached to the 5’ end of the genome rather than a cap.
12. I am a small, ssDNA virus. My genome has inverted repeats at the end which fold up and resemble a dog bone.
13. _____ viral genomes have the ability to immediately produce protein, as their genomes are mRNAs.
15. Class VI viruses, known as ___, convert their RNA genome into dsDNA within the host cell.
16. Rescue of ___ RNA viruses requires transfection of multiple plasmids.
19. Unlike other class V viruses, I replicate my viral genome in the nucleus.