Across
- 10. In adults, a severe Vitamin D deficiency results in this
- 11. Vitamin C is responsible for the _______ of Pro and Lys residues, which are essential for collagen stability
- 12. A 1 year old girl is brought to your clinic. She was exclusively breastfed for her first year of life and presents with widened wrists, a prominent forehead, and bowed legs. A likely diagnosis would be ____
- 15. _____ acid is the transcriptionally active form of Vitamin A
- 16. Beta-______ aka provitamin A is the form of Vitamin A found in plant sources
- 17. The ____-soluble vitamins are K, A, D and E
- 18. When serum calcidiol (25-OH) levels are low, this hormone is expected to be high
- 19. _____ is a competitive inhibitor of Vitamin K, and has an anticoagulation effect
- 21. Vitamins C and E act as ______ and take care of reactive oxygen species (ROS)
- 23. Severe complications of _____ acid deficiency are spina bifida and anencephaly in newborns
- 24. aka pre-formed Vitamin A, is the form of Vitamin A found in animal sources
- 25. The enzyme dihydrofolate reductase is inhibited by this drug
Down
- 1. This type of anemia can be caused by deficiencies in folic acid or Vitamin B12
- 2. This Vitamin is a precursor of AcetylcoA
- 3. Pantothenic acid is important for the _____ acid synthesis pathway
- 4. A complication of Vitamin C deficiency is this condition
- 5. The most common cause of Vitamin B12 deficiency is this
- 6. Vitamins B9 and B12 work together in synthesis of _____
- 7. Folic acid is incredibly important since it helps synthesize ____
- 8. The transcriptionally active form of Vitamin D is called _____, also written as (1,25-diOH-D3)
- 9. _____ pyrophosphate (TPP) is a coenzyme involved in oxidative decarboxylation of α-keto acids (branched ones too)
- 13. Unlike other water-soluble vitamins, B12 (also known as this) can be stored in the body; pernicious anemia can take years to develop
- 14. In the clotting cascade, Vitamin K acts as an essential cofactor for post-translational carboxylation of ______ residues
- 20. Elevated serum _____ (amino acid) and formiminoglutamate indicate folate deficiency
- 22. Rickets only occurs in _____, since their growth plates are still open
