Week 15 - DISORDERS OF SECONDARY HEMOSTASIS

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Across
  1. 1. condition characterized by widespread microthrombi production
  2. 4. inhibitory substance produced in autoimmune disorders affecting coagulation
  3. 7. oral anticoagulant belonging to coumarin group
  4. 8. best used to detect fibrin degradation products
  5. 11. inherited disorder caused by factor XI deficiency
  6. 13. venom based test used to assess factor X activity
  7. 14. common pathway clotting factor synthesized in liver and vitamin K dependent
  8. 17. Laboratory test that remains normal in factor XI deficiency
  9. 18. coagulation pathway that begins with tissue factor
  10. 20. disorder characterized by decreased synthesis of coagulation factors due to liver disease
  11. 22. factor assay used to monitor replacement therapy in hemophilia B
  12. 23. contact factor also known as the Fletcher factor
  13. 25. laboratory test prolonged in extrinsic pathway defects
  14. 26. plasma product used to replace multiple coagulation factors
  15. 29. rare inherited disorder marked by absence of clot stabilization
  16. 31. abnormal fibrinogen disorder inherited as an autosomal dominant trait
  17. 32. plasma product rich in factor VIII and fibrinogen
  18. 34. condition where platelet function is impaired, despite normal count due to transfusion
  19. 36. most frequently inherited bleeding disorder
Down
  1. 1. fibrinogen Abnormality resulting in weak polymerization
  2. 2. clotting factor measured using chromogenic substrate methods in the extrinsic pathway
  3. 3. anticoagulant drug that enhances at antithrombin III activity
  4. 5. plasma protein deficient in Fitzgerald factor deficiency
  5. 6. disorder, characterized by absence of fibrinogen
  6. 8. disorder caused by deficiency of factor VII
  7. 9. laboratory test prolonged in intrinsic pathway disorders
  8. 10. laboratory test that measures conversion of fibrinogen to fibrin
  9. 12. anticoagulant protein affected by coumarin therapy
  10. 15. anticoagulant drug administered intravenously
  11. 16. inherited disorder due to factor VIII deficiency
  12. 19. severe inherited bleeding disorder known as classic hemophilia
  13. 21. inherited condition with reduced but detectable fibrinogen levels
  14. 24. vitamin necessary for activation of factors II, VII, IX and X
  15. 26. vitamin K dependent clotting factor deficient in hemophilia V
  16. 27. most common inherited thrombophilia caused by APC resistance
  17. 28. lab abnormality seen in mass massive transfusion due to citrate excess
  18. 29. rare disorder with unstable feeding clot due to factor XIII deficiency
  19. 30. protein required for platelet adhesion and carrier of factor VIII
  20. 33. mutation involving guanine to adenine in substitution in factor V gene
  21. 35. antibody medicated inhibitor seen in acquired coagulation disorders