Across
- 1. part of spleen where immune induction occurs; rich in lymphocytes
- 6. act as filters to trap antigens
- 10. inductive and effector site of intestinal immune response
- 12. Two species in which Peyer’s patches DO NOT undergo involution (alphabetical, no space)
- 14. primary lymphoid organ for B cell development in ruminants, pigs, dogs, and rabbit; found in ileum
- 15. part of lymph cortex where B lymphocytes are found
- 17. cells that are required for the development of lymphoid tissues
- 19. Truth/False Surgical removal of a few lymph nodes does not impair immune capability
- 22. part of spleen that filters blood and stores RBC
- 23. facilitates the interaction between DCs and antigen-sensitive T and B cells
- 25. ______ lymphoid organs: spleen, lymph nodes, non-encapsulated lymphoid tissue, Peyer’s patches
Down
- 2. ______ selection: thymocytes with proper MHC II/AG complex with moderate affinity are allowed to live
- 3. ____ cells found in secondary lymphoid organs trap and process and present antigens
- 4. ______ selection: apoptosis of thymocytes that bind strongly to self-antigens or those that cannot bind at all
- 5. T lymphocytes develop in the bone marrow and mature in the ______
- 7. the thymus undergoes ____ in adults
- 8. T cells and DCs are mainly found in _______ in a lymph node
- 9. hematopoietic organ that gives rise to all blood cells
- 11. cells first produced in the yolk sac, fetal omentum, and liver
- 13. filters blood, stores blood, platelets and recycles iron
- 16. cells found in cortex of thymus
- 18. Truth/false Primary lymphoid organs are usually sites of lymphocyte interaction with microbial antigens
- 20. localized to mucosal surfaces and respond to molecules secreted by epithelial cells; immune cells that belong to the lymphoid lineage
- 21. Main location of lymphoid cell production in adults
- 24. ______ lymphoid organs: thymus, bone marrow, Bursa of Fabricius in birds