Across
- 4. In the DEVOTE study, degludec was _________ to glargine in regard to severe hypoglycaemia in type 2 diabetic patients with high cardiovascular risk.
- 5. The ______trial reported that bariatric surgery plus intensive medical therapy was superior to the latter alone in improving glycaemic control, cardiovascular risk factors and quality of life after 5 years in moderate- and severely-obese patients with type 2 diabetes.
- 8. Degludec is an an _______acting insulin.
- 11. The _________ study demonstrates that empagliflozin reduces the risk of non-fatal myocardial infarction and cardiovascular death and slows the progression of diabetic kidney disease.
Down
- 1. In middle-income countries, diabetes accounts for one-____ of all deaths in adult patients.
- 2. In _______, semaglutide lowered cardiovascular death and non-fatal events in patients with type 2 diabetes.
- 3. Reduced _______ adipose tissue storage capacity is a key determinant of insulin-resistance and that this link is mediated by specific and multiple genetic factors.
- 6. In middle- and low-income countries (>25%), mortality is ____-times higher amongst those with vs those without diabetes.
- 7. In more affluent countries, recent studies demonstrate a ____ in all-cause mortality and the incidence of cardiovascular complications in patients with type 2 diabetes.
- 9. In the ________ study, liraglutide lowered cardiovascular death and non-fatal events in patients with type 2 diabetes.
- 10. _______ reported a cardiovascular benefit for canagliflozin.