Across
- 2. Cells with limited self-renewal and differentiation capacity that can give rise to more specialized cell types.
- 4. The use of stem cells obtained from a healthy donor to treat a patient, with a potential risk of immune rejection.
- 7. The process by which hematopoietic progenitor cells in the bone marrow generate mature blood cells.
- 8. A therapy that uses a patient’s own cells for treatment, reducing the risk of immune rejection.
- 10. A procedure in which stem cells are administered to a patient to repair or replace damaged tissues.
- 11. The process by which stem cells transform into specialized cells with specific functions in the body.
- 13. The process by which transplanted cells establish, proliferate, and contribute to tissue regeneration in the recipient.
- 14. Cellular communication mechanisms that control proliferation, differentiation, and cellular functions through pathways such as Wnt, AKT, and Notch.
- 15. The cellular and molecular environment that regulates stem cell activity through growth factors, cytokines, and intercellular signals.
Down
- 1. A technique in which somatic cells are converted into induced pluripotent stem cells (iPSCs) by expressing specific transcription factors.
- 3. The ability of stem cells to repair and replace damaged or deteriorated cells to restore tissue and cellular function.
- 5. The ability of stem cells, especially mesenchymal stem cells, to regulate immune responses and reduce inflammation in various diseases.
- 6. The ability of pluripotent stem cells (hPSCs) to self-renew and differentiate into various cell types, including the three germ layers.
- 9. Factors Molecules such as VEGF, FGF, and PDGF that regulate cell proliferation, differentiation, and migration in stem cell-based therapies.
- 12. The tissue of origin for mesenchymal stem cells (MSCs), which can differentiate into mesenchymal lineages such as osteoblasts, chondrocytes, and adipocytes.