Anaesthetics

3. most commonly used IV general anaesthetic; GABAa allosteric modulator; suitable for maintenance
4. a measure of potency for general anaesthesia; the anaesthetic concentration required to abolish response to a surgical incision in 50% of patients
7. used to speed up anaesthesia via other anaesthetic agents
8. dissociative anaesthetic; may not induce FULL unconsciousness but has a state of full analgesia, amnesia and little awareness; NMDA antagonist; suitable for maintenance; IV general anaesthetic
10. VGNaC blocker; preferred for spinal analgesia; as an epidural
11. what form of a drug is impermeable to the cell membrane
12. widely used GABAa positive modulator; inhalation anaesthetic
13. IV general anaesthetic; not for maintenance; non- analgesic effect
14. low lipophilicity; GABAa positive modulator; inhalation anaesthetic

1. after entering the cell, what must a drug bind to, to attach to the voltage gated Na+ channel
2. VGNaC blocker; highly lipophilic & rapidly metabolised by plasma esterases, this minimises the systemic spread and makes it good for topical application
5. VGNaC blocker; the most common drug used for general purpose
6. partially metabolised GABAa positive modulator; risk of renal toxicity
9. ultra short acting barbiturate; not suitable for maintenance; IV general anaesthetic