Across
- 3. These kind of molecules can be expressed by any time of cell (two words).
- 5. These vaccines have been made against weakened forms of the pathogen that are unable to cause disease in healthy individual but retain antigens that generate memory.
- 7. These vaccines have been made from isolating non-dangerous proteins from a pathogen that can elicit an immune response but not cause infection.
- 8. These plasma B cells are produced in germinal centers and later reside in bone marrow, producing small amount of antibodies over a long period of time (two words).
- 10. These are the secreted proteins produced by dendritic cells (DCs) after leaving the battle site (the area of infection).
- 12. These vaccines have been made from parts of toxins that have been modified or weakened but otherwise “appear” normal.
- 16. The process by which an infected cell’s DNA is destroyed by the cells own enzymes.
- 19. T cells whose job is to downregulate the immune system.
- 22. This type of T cell inspects the peptides presented on class I MHC molecules.
- 23. Both CTLs and NK cells can kill infected cells using perforin/granzyme and ____.
- 25. IL-6 and TGFb are cytokines that cause uncommitted T helper cells to become this class of T helper cell(two letters followed by two numbers).
- 26. The idea that an exogenous antigen could be displayed by a class I MHC molecule (two words).
- 28. These T cells expresses only CD4 or CD8 rather than both (two words).
- 30. These vaccines have been made from whole organisms that have been “killed” chemically but otherwise “appear” normal (two words).
- 31. In order to prevent an autoimmune disease, this process is about keeping T cells that recognize foreign peptides as opposed to self peptides (two words).
- 32. These vaccines have been made against viruses using genetic engineering to isolate specific viral proteins.
Down
- 1. T cells are born in the bone marrow and are taught self tolerance initially when they leave the bone marrow and move to this location.
- 2. This is the place where B cells are educated to tolerate self (two words).
- 4. The protein molecules that display lipids instead of the classical peptides (two letters followed by a number).
- 6. These vaccines have been made from organisms that cannot cause disease but otherwise “appear” normal.
- 9. These types of NK, T, and B cells all go through some level of “tolerance” training.
- 11. The portion of the invariant chain that occupies the class II MHC groove in an endosome.
- 13. If an NK cell comes upon another cell in your body that produced no class I MHC molecules, it will kill that cell because it is missing this principle (two words).
- 14. The concept that immune cells can recall pathogens they have seen in the past.
- 15. This type of protein is presented by class II MHC molecules and are presented to helper T cells.
- 16. These molecules are activated T cells have license to visit specific areas of the body, and their ability to visit a site. They are also the “passport” that Virgin T cells have that allow them to visit specific sites in the body.
- 17. lived These plasma B cells are produced in lymphoid follicles and the early stages of invasion and travel to the bone marrow to produce massive quantities of antibodies (two words).
- 18. These memory T cells stay in the secondary lymphoid organs and wait to produce activated T cells in the future.
- 20. The group of chemical messengers secreted by helper T cells that serve to provide instructions to the rest of the immune system.
- 21. The main purpose of this is to organize and concentrate antigen presentation to increase the chance of lymphocytes finding their cognate antigen (two words).
- 24. These vaccines use genetic engineering to trick a virus that can’t hurt us into putting a single gene from a pathogenic microbe in our cells. That gene will then make the one protein from the pathogenic microbe inside our cells, but since it’s only one protein it can’t hurt people.
- 27. IL-4 is a cytokine that causes uncommitted T helper cells to become this class of T helper cell (two letters followed by one number).
- 29. This type of protein is presented by class I MHC molecules and are presented to killer T cells.