Across
- 3. movement of cells toward a chemical signal
- 5. antibody-mediated clumping of pathogens
- 9. microbial molecules recognized by innate immune receptors (abbreviation, singular)
- 11. T cell-rich zone in lymph nodes
- 13. complement pathway triggered by lectins such as MBL
- 15. antibody region that determines class and function
- 18. first word in MBL that triggers complement activation
- 19. prostaglandin that raises hypothalamic temperature setpoint
- 20. ability of lymphocytes to recognize a specific antigen
- 23. cell derived from B cell that secretes antibodies
- 24. substance that induces fever, like IL-1 or IL-6
- 25. type of basement membrane in lymphatic capillaries
- 31. substance that activates adaptive immune defenses
- 34. molecules that present peptide antigens to T cells (abbreviation)
- 35. antibody region that binds specific antigens
- 37. T cell that activates other immune cells (CD4+)
- 38. segment between valves in collecting lymphatic vessels
- 40. lymphoid follicles with germinal centers
- 41. chemical from mast cells that increases vasodilation and permeability
- 42. professional antigen-presenting cells
- 43. protein complex that forms pores in microbe membranes (abbreviation)
Down
- 1. cells that transport antigens from intestinal lumen to Peyer’s patches
- 2. lymphoid follicles with naïve B cells
- 3. T cell that kills infected or abnormal cells (CD8+)
- 4. type of thymic selection eliminating self-reactive T cells
- 6. node structures that receive lymph from collecting lymphatic vessels
- 7. antibody function that blocks pathogen binding to host
- 8. junction; connect lymphatic endothelial cells in lymphatic capillaries
- 10. long-lived lymphocyte that responds quickly upon re-exposure
- 12. molecules like antibodies or C3b that tag pathogens for phagocytosis
- 14. induces artificially acquired active humoral immunity
- 16. type of thymic selection ensuring T cells recognize MHC
- 17. first word in the abbreviation for PRRs
- 19. accumulation of fluid in tissues causing swelling
- 21. coating of pathogens to enhance phagocytosis
- 22. part of an antigen recognized by immune receptors (also known as antigenic determinant)
- 26. group of identical B or T cells with same antigen specificity
- 27. lymphatic duct that drains lymph from most of the body
- 28. veins where lymph enters venous circulation
- 29. protein system that enhances innate immune responses
- 30. complement pathway triggered by spontaneous activation of C3b
- 32. antiviral cytokines released by infected cells
- 33. migration of leukocytes through vessel walls into tissues
- 36. Immunoglobulin E is involved in this and parasite defense
- 37. type of immunity involving plasma cells and antibodies
- 39. complement pathway activated by antigen–antibody complexes