Biology of a Cancer Cell

2. the cancer that is the leading killer in both men and women in recent years.
3. Tissue Inhibitors of Metalloproteases.
6. Histone deacetyl transferases
7. rapid response immunity; most animal species do not possess this immunity
8. named after a crab, when tumor cells become malignant
9. binds to and activates caspase 9 (initiating caspase) for the Intrinsic Pathway
11. sister chromatids segregate towards opposite poles
13. critical in activating the WNT pathway in colon cancer, 80% of all colon cancers have mutations in this gene
14. group of proteases capable of eating a cell within
16. cancers of the blood
18. genes that, when hyperactive, promote cancer development
22. the formation of new blood vessels
23. immunity that is ‘educated’ from a previous encounter
24. “disassembly” of the cell

1. when a tumor mass is contained, and cells are not able to wander.
4. process where cancer cells leave the tumor and enter the bloodstream through small vessels
5. uncontrolled cells growing in a solid mass
6. abnormal increase in amount of normal looking cells in a tissue
10. Hereditary Non-Polyposis Colorectal Cancer
12. programmed cell death
15. the study of the distribution and prevalence of disease, but does NOT establish cause
17. Inhibition the signal that stops cells from dividing when in contact with their neighboring cells
19. Matrix metalloproteinases
20. RNA containing multi-subunit, that adds DNA sequences to the chromosome’s 3’ end.
21. complete loss of differentiation