Across
- 6. Process where solid drug particles dissolve in gastrointestinal fluids.
- 7. Ability of a drug to cross biological membranes.
- 8. Fraction of an administered drug reaching systemic circulation unchanged.
- 9. Movement of drug from site of administration into bloodstream.
- 10. Removal of drug and metabolites through urine, bile, or feces.
Down
- 1. Volume of plasma cleared of drug per unit time.
- 2. Reversible transfer of drug from blood to body tissues.
- 3. Time required for plasma drug concentration to decrease by fifty percent.
- 4. Biotransformation of drugs mainly occurring in the liver.
- 5. Hepatic metabolism reducing drug concentration before systemic circulation.