Across
- 5. Type of lymphocyte that is predominately made in the thymus. It plays a central role in cell-mediated immunity.
- 8. The term that describes the growth of microfilaments. Subunits are added onto one end of the filament while subunits are removed from the other end
- 9. Drug that can be used to stop cell crawling by inhibiting RNA polymerase and stabilizing filaments.
- 13. Form of immunity mediated by circulating antibodies, which coat the antigens and target them for destruction
- 15. The protein subunit of microtubules
- 18. Anchoring cell-cell junction, usually formed between two epithelial cells.
- 20. Moves cargo on microtubules in the plus direction. Their linker domain is responsible for the size step they take.
- 21. Motor proteins that move along actin filaments
- 23. Addition of one or more sugars to a protein or lipid molecule
- 24. Type of vaccine made from a toxin that has been chemically modified.
- 27. The primary function of these proteins is to facilitate membrane fusion.
- 28. Complex of proteins that nucleates actin filament growth from the minus end
- 29. Protein that plays a major role in the formation of coated vesicles.
- 30. A drug that can be used as an anti-cancer drug. It binds to and stabilizes microtubules, causing a net increase in tubulin polymerization.
- 32. This kind of transport delivers proteins from ER to the Golgi in COPII vesicles
- 33. A ER unfolded protein response that involves a cytoplasmic splicing process.
- 34. Protein that binds to a GTPase and activates it by stimulating it to release its tightly bound GDP, allowing it to bind GTP in its place.
- 35. This kind of junction seals gaps between cells to create epithelial sheets
- 36. Type of vaccine created by reducing the virulence of a pathogen.
- 37. Type of leukocyte that appears in inflammatory responses.
Down
- 1. Enzymes that can bind and hydrolyze guanosine triphosphate (GTP)
- 2. Drug that can be used as an anti-cancer drug. It binds to and stabilizes free tubulin which prevents polymerization.
- 3. Intermediate filament-type proteins that are the major building blocks of the nuclear lamina.
- 4. Type of cell that processes antigen material and presents it on the cell surface to the T cells
- 6. A local response of a tissue that is general and non-specific to tissue damage. It is characterized by tissue redness, swelling, heat, and pain.
- 7. Cell-cell junction that seals adjacent epithelial cells together, preventing the passage of most dissolved molecules form one side of the epithelial sheet to the other.
- 10. Type of lymphocyte that makes antibodies.
- 11. Bundle of microtubules and associated proteins that forms the core of a cilium or a flagellum in eukaryotic cells and is responsible for their movements
- 12. The kind of cells that the extracellular matrix arises from.
- 14. Membrane-bounded organelle in eukaryotic cells containing digestive enzymes. It is normally maintained at a pH below 5.
- 16. Target peptide sequence in the amino acid structure of a protein which prevents the protein from being secreted from the ER
- 17. Actin-binding protein which allows for the addition to the plus end
- 19. Inhibits viral spread from cell to cell and activates natural killer cells to kill virus-infected cells
- 22. Type of cell that secretes mucus and protects against microbes
- 25. The aggregation disease which results from a build-up of amyloid plaques.
- 26. This type of immunity is the third line of defense. It is immunity that occurs after exposure to an antigen either from a pathogen or a vaccination. This part of the immune system is activated when the innate immune response is insufficient to control an infection.
- 31. A ER unfolded protein response that involves regulated removal of the sensor protein from the membrane. Its sensor is also a transcription factor.