Across
- 2. Cause cancer when carrying a loss-of-function mutation
- 3. This type of cell signaling involves cells proliferating in response to mitogens released by neighboring cells
- 6. Intercellular channels that facilitate communication among cells in tissue by allowing ions and small molecules to move between adjacent cells
- 9. The state where cells exit the cell cycle permanently and eventually die
- 10. Give rise to oncogenes that cause cancer by carrying a gain-of-function mutation
- 11. Commonly used method to measure tissue stiffness
- 12. Type of stem cells found in early embryos
- 15. The gate-keeper for G1-to-S transition
- 18. The phase in microbial cell growth where cells double exponentially with time with the maximum growth rate
- 19. Condition of having an abnormal number of chromosomes
- 20. Cultured stem cells derived from differentiated adult tissues
- 22. Commonly used scaffold of networks of polymers that swell in water to form a gel-like structure
Down
- 1. Provides tensile strength to tissues and consists of a triple helix made of the repetitious amino acid sequence glycine-X-Y
- 4. Mediate adhesion between neighboring cells and between cells and the ECM and help in stress distribution in tissue
- 5. This pathway plays a key role in regulating the proliferation of intestinal stem cells
- 7. A process by which cells become more specialized
- 8. This holds sister chromatids together during metaphase
- 13. Set the boundary between the apical and basal domains of plasma membrane in epithelial cells
- 14. This type of cell signaling involves hormones released by endocrine cells traveling through the blood to reach a target cell
- 16. Composed of a core protein and covalently attached GAGs, providing compressive strength to tissues
- 17. This type of cell signaling responds to signals from the same cell
- 21. This type of cell signaling propagates action potential along nerve axons and through synapses