Cell Metabolism

3. any metabolic process that involves the breakdown of complex molecules (such as proteins or lipids) and the release of energy
7. abbreviation for an essential metabolite; methyl group donor involved in the methylation of DNA, RNA and histones
9. serine/threonine kinase; interacts with Akt, a key player in mammalian metabolism
10. Term employed to describe a cellular system used to translocate electrons across impermeable membranes
13. By-products of normal oxygen metabolism; can cause irreversible damage to DNA
14. State of scarcity of a metabolite, like glucose
15. term applied to particular biochemical pathways in which metabolites are newly biosynthesized

1. The ______ effect; tumor cell reliance on glycolysis rather than oxidation to meet metabolic needs
2. electron donating molecule; used by enzymes to synthesize large biomolecules
4. final step of cellular respiration; a series of redox reactions involving the flow of electrons along a series of membrane-bound proteins, coupled with the generation of Adenosine triphosphate (ATP)
5. Key part of an important TCA cycle intermediate; consists of a β-mercaptoethylamine group linked to the vitamin pantothenic acid (B5) through an amide linkage[3] and 3'-phosphorylated ADP
6. endogenous intermediates of metabolism that aberrantly accumulate in cancer cells
8. A central cellular respiration pathway, produces NADH and FADH2, occurs in the mitochondria
11. deprivation of oxygen, can drive tumor progression
12. most abundant free amino acid in circulation; very important in cancer metabolism
14. major eukaryotic lipid, named after a legendary mythological creature that creates riddles