Across
- 5. " " at specified time. Both old and new, bigger number
- 6. more than one microbe
- 9. most severe
- 11. where it is aquired
- 14. diseases caught from animals
- 15. when symptoms subside
- 17. skin, adjacent mucous membranes, upper respiratory tract, gastrointestinal tract
- 20. capable of causing disease in healthy person with normal immune defenses
- 23. causes blood clotting
- 25. cause disease when hosts defenses are compromised
- 27. develops rapidly, short time
- 28. the total sum of all microbes
- 30. long-term or permanent damage to organs from infectious disease
- 32. human microbe project, like human genome project, aims to characterize micorbes on human bodies when healthy vs. in diseased state
- 33. limulus amebocyte lysate assay, in blood of horshow grabs, coagulates when in contact with endotoxins (amebocytes lyse)
- 34. some microbes survive phagocyte ex. mycobacterium tuberculosis
- 37. a microbe whose relationship to host is parasitic and results in infection and disease
- 39. the minimum number of microbes necessary to cause infection
- 41. a dormant state of microbes in chronic infectious diseases
- 42. present in population frequently (cold)
- 44. study of frequency and distribution of diseases and other health-related factors
- 45. breaks down mucus membranes
- 47. deviation from health that results when cumulative effects of infection damage
- 49. microbes get past host defences, enter tissues, and multiply
- 50. like hemolysins disrupts cell membrane of RBC'S
- 54. pneumonia, gastro illness, urniary tract inf., bloodstream inf., surgical site (closridiodes difficile, staph aureus, klesiella species, escherichia coli, enterococcus species
- 55. attaching to host cells (depends on binding between specific molecules on both the host and pathogen)
- 56. secreted by microbes to break down and inlict damage on tissues
- 57. unlikely to to be displaced by incoming microbes (hostile to others)
- 59. coming from within human host to cause infection
Down
- 1. severity of a disease (establish and cause damage)
- 2. number of persons afflicted
- 3. develops slowy, continues
- 4. number of deaths
- 7. lungs (lower respiratory tract), bladder, breast and milk, amniotic fluid
- 8. number of people who develop disease in a particular time
- 10. causing disease (enzymes or endotoxins, exotoxins, causing septic shock)
- 12. occurs occasionally (typhoid)
- 13. not spread from host to another (tetanus)
- 16. LPS, gram- (fever, inflammation, hemorrage, diarrhea)
- 18. becoming established through portal of entry (need correct portal ex. flu and mucus)
- 19. healthcare associated infections. Affects 5-15% of hospital patients (compromised, collection point for pathogens, clothing, medical equipment, furniture, doctors, visitors, air, water)
- 21. " " throughout body (sepsis)
- 22. time b/w initial infection and symptoms
- 24. recovery
- 26. an organisms potential to cause disease
- 29. acquired by many people in an area in short period
- 31. where pathogens originate (water, dirt, people, animals)
- 35. microo. limited to small area (boil)
- 36. spreads from host to another (chicken pox)
- 37. early, mild symptoms
- 38. and characteristic that contibutes to abilty to establish or cause damage
- 40. vating the host usually where they came in
- 43. surviving host defenses
- 46. organisms coming in from outside the body
- 48. needs vaginal birth for microbiome (lactobacillus)
- 51. opportunistic pathogen causes another infection with weakened immune system (pneumonia after AIDS)
- 52. inactive until active
- 53. acute infection that causes initial illness
- 58. worlwide (AIDS, COVID)