Across
- 1. downregulation of this surface protein makes tumor cells susceptible to NK cells
- 3. cancers of epithelial cells
- 6. a term that means control and elimination of malignant cells by the immune system
- 7. cancer of the immune system involving circulating cells
- 9. the branch of medicine that deals with tumors
- 10. tumors that are encapsulated, localized, and limited in size (no need for the word ‘tumor’)
- 11. uncontrolled growth of cells
- 13. the inhibitory receptor on T cells for B7
- 14. therapy using T cells expressing chimeric antigen receptors (CARs)
- 15. a large number of mutations present in diverse genes which play no role in tumorigenesis (no need to include the word ‘mutations’)
Down
- 2. tumors that stop expressing the antigens that are the targets of immune attack
- 4. When cluster of cancerous cells dislodge from the primary site and travel via blood or lymphatic vessels to distant tissues
- 5. the approach of stimulating immune responses by a drug that inhibits the inhibitors
- 8. cancer involving bone marrow
- 12. chemical produced by macrophages that helps in killing on tumor cells