Across
- 1. cytogenic probe analysis designed to visualize the entire complement of metaphase chromosomes, with unique colors for each chromosome
- 5. probes that bind to telomeres
- 9. FISH probes designed to detect translocations where there are multiple possible partners
- 11. a type of mutation involving alterations in the number of chromosomes
- 12. type of translocation involving movement of most of one entire chromosome to the centromere of another chromosome
- 13. array of intact chromosomes displayed upon hypotonic lysis of a nucleus
- 14. probes that bind to centromeres
- 16. a difference in DNA sequence found in less than 1% of the population
- 20. FISH probes designed to detect translocations and their reciprocal products
- 21. having 3 of each chromosome
Down
- 2. a complete set of metaphase chromosomes of a cell
- 3. a type of mutation involving alterations in the primary DNA sequence
- 4. abnormal chromosome comprissed of rearranged parts from two or more unidentified chromosomes joined to a normal chromosome
- 6. a type of mutation involving structural changes in chromosomes
- 7. a difference in DNA sequence found in more than 1% of the population
- 8. pattern on chromosomes after staining with Giemsa
- 10. type of inversion including the centromere
- 14. method to deletions or amplifications in DNA
- 15. type of translocation involving the exchange of DNA between separate chromosomes with no gain or loss of genetic material
- 17. introchromosomal breakage, reversal and reunion of genetic material
- 18. basic protein that associates with DNA during compaction
- 19. having an aberrant number of chromosomes per nucleus