Across
- 3. Can you combine glicalzide MR with metformin and Forxiga
- 6. Which SU binds to the SU receptors in the heart
- 7. Is Empagliflozin indicated or contra-indicated in patients with CKD stage 4( eGFR less than 30ml/min/1.73m2)
- 8. Name one of the trials included in the Mbanya meta-analysis showing the lower incidence of hypoglycaemia on Gliclazide versus other SU`s
- 10. The mean annual costs for a T2D patient with nephropathy increases dramatically by what percentage
- 13. Who put the Guidance for Industry together to establish the safety of new anti-diabetic therapies
- 14. What can the primary endpoint of CVOT`s consist of
- 15. Which DPP-4i has shown renal protection in CVOT`s in T2D patients
- 17. Coronary heart disease, cerebrovascular disease or peripheral arterial disease are also known as what type of CV disease
- 19. Which SGLT-2i was compared to placebo in the EMPA-REG outcome trial
- 20. What percentage regression to normoalbuminuria was seen in the ADVANCE Study,with a strategy based on Gliclazide modified release
- 21. Which SU has shown to achieve greater HbA1C reductions than DPP-4i`s, SGLT-2i`s and other SU`s in the Jia Meta-Analysis
- 22. In up to what % of patients with T2D is ASCVD,HF and CKD present
- 23. When albumin is passed into the urine as a result of damaged kidneys, what is it called?
- 24. What is the name of the CVOT that compares Linagliptin with Glimepiride
Down
- 1. Name one meta-analysis that has shown better CV safety of Gliclazide relative to other SU`s
- 2. How many SGLT-2i CVOT`s have shown a significant reduction in the risk of hospitalisation for heart failure
- 4. Which SU was compared to Gliclazide MR in the GUIDE Study
- 5. Predictor of outcomes and microvascular complications
- 9. Does diabetic kidney disease increase or decrease the risk of hypoglycaemia
- 11. Name one of the challenges when managing patients with diabetic kidney disease
- 12. What DPP-4i in the SAVOR -TIMI trial has shown an increase in hospitalisation for heart failure
- 16. More than ?(how many) patients were included in the EASY-Dia Observational Study
- 18. Which side-effect of anti-diabetic agents is considered an indirect contributor to CV risk
- 22. Approximately what percentage of adults have signs of CKD before diagnosis of diabetes