Across
- 4. Autoantibodies against organs, tissues, intracellular materials, caused by viral infection and loss of normal immune response suppression
- 5. Type of hypersensitivity involving Rh or other blood antigens
- 6. Type of hypersensitivity involving reaction of soluble antigen with antibody, and deposition of resulting complexes in various tissues
- 8. Released by mast cells in response to IgE binding during type 1 allergic response
- 11. When Group A Strep antibody/antigen complex settles in kidney, complement activation leads to infiltration of neutrophils, kidney damage results
- 14. The study of disease states associated with over-reactivity or under-reactivity of the immune response
- 15. Binds to mast cells during type 1 allergy
Down
- 1. Weakened immune response that results in recurrent, overwhelming infections by opportunistic microbes
- 2. Granulocyte involved in helminth response, stimulated by histamine to release cytokines
- 3. Chronic localized allergy like hay fever or asthma (aka allergic rhinitis)
- 7. Most profuse and fast-acting allergic mediator, constricts small bronchi and dilates blood vessels, stimulates eosinophils to release inflammatory cytokines
- 9. A swift reaction to allergens, sudden and massive release of chemicals into tissues and blood
- 10. Graft attacks host tissue bearing foreign MHC markers, occurs within 100-300 days of graft
- 12. Type of hypersensitivity, "delayed", involves T-cells, they respond to transplanted foreign cells
- 13. clicking, bubbling, or rattling sounds in lungs as a result of asthma