Extracellular matrix

6. - Inactive intracellular precursor form of collagen
7. - Triple helical basic structural unit formed after cleavage of procollagen
10. - Glycoprotein defective in Marfan syndrome
12. - Autosomal recessive disorder caused by CFTR mutation leading to thick mucus
14. - Major structural protein of extracellular matrix and most abundant protein in the body
15. - Long unbranched polysaccharides present in proteoglycans

1. - Copper containing enzyme responsible for collagen cross linking
2. - GAG lacking sulfate groups and important for lubrication
3. - Major glycoprotein of basement membrane responsible for selective filtration
4. - ECM glycoprotein involved in cell adhesion and metastasis prevention
5. - Special arrangement of collagen fibers helping in mineralization
8. - Infectious misfolded protein causing spongiform encephalopathy
9. - Protein that provides elasticity and recoil to tissues like lungs and blood vessels
11. - Syndrome characterized by tall stature, long fingers and aortic aneurysm
13. - Vitamin C deficiency disorder causing defective hydroxylation of collagen