Across
- 1. abnormal development of the cartilaginous and osseous tissues resulting in bones that appear shortened, thin, deformed, or that fail to form at all.
- 3. abducted thumb, associated with dwarfism
- 6. second most common lethal type, decreased bone mineralization, abnormal bone formation
- 7. shortening of the entire limb
- 10. club hand
- 13. mildest type of OI
- 14. most severe type of OI
- 16. extra digits on hand or foot
- 17. clubfoot
- 19. permanent flexion of finger
- 20. shortening of the distal segments (hands, feet)
- 21. bent limbs, short and bowing of the long bones
- 23. shortening of the middle segments (radius, ulna, tib, fib)
Down
- 2. lobster claw split hand or foot
- 4. severe micromelia, polydactyly, 3 types
- 5. increased frequency in the Amish community, short limbs, polydactyly, cardiac defects, (chondroectodermal dysplasia)
- 8. permanent incurvature of a finger (usually 5th: pinky), common in T21
- 9. most common lethal form of skeletal dysplasia, severe micromelia, decreased thoaric circumference, short curved "telephone reciever" femurs, flat vertebral bodies, champagne cork appearing abdomen, cloverleaf skull
- 11. exaggerated gap between 1st and 2nd digits
- 12. shortening of the proximal long bones (femur and humerus)
- 15. cutaneous or osseous fusion of digits
- 18. connective tissue disorder caused by defects in type 1 collagen found in skin, ligaments, tendons, and bone, results in multiple fractures, hypomineralization, and brittle bones, 4 main types ranging in severity
- 22. most common nonlethal form, trident configuration of hands, enlarged head, low nasal bone, rhizomelia, 2 forms