Across
- 5. Study of drug movement through the body.
- 7. tolerance Reduced effect of drug over time.
- 8. Maximum effect a drug can produce.
- 9. Amount of drug needed for effect.
- 12. of distribution Hypothetical space drug occupies in the body.
- 13. dose Large initial dose to quickly reach therapeutic level.
- 15. Drug that blocks receptors.
- 16. Rapid decrease in drug response.
- 20. reaction Unpredictable, unusual drug reaction.
- 21. Biochemical alteration of drugs in the liver.
- 22. Constant drug concentration in the bloodstream.
- 25. Drug that activates receptors.
- 26. dose Dose to maintain drug level within therapeutic range.
- 28. effect Drug metabolism in liver before reaching circulation.
- 29. inhibition Decrease in enzyme activity, increasing drug levels.
Down
- 1. Study of genetic influence on drug response.
- 2. Study of drug effects on the body.
- 3. Dispersion of drug throughout the body.
- 4. Fraction of administered drug that reaches systemic circulation.
- 6. window Range between effective and toxic dose.
- 10. protein binding Drug binding to albumin affecting distribution.
- 11. Time for drug concentration to reduce by half.
- 14. index Ratio of toxic dose to effective dose.
- 15. Movement of drug from site of administration to bloodstream.
- 17. Strength of binding between drug and receptor.
- 18. Inactive compound converted to active form in body.
- 19. induction Increase in enzyme activity, reducing drug levels.
- 23. effect Harmful reaction to a drug.
- 24. Removal of drugs from the body, mainly by kidneys.
- 27. effect Unintended effect of a drug at therapeutic dose.