Across
- 1. a blood test marker for inflammation in the body
- 3. group of genes that code for proteins found on the surfaces of cells that help the immune system recognize foreign substances
- 6. these are secreted by plasma cells and that function as antibodies in the immune response by binding with specific antigen
- 9. lymphocyte that matures in the thymus
- 11. transcription factor expressed in Treg cells that is needed for their function
- 13. cell surface ligands for leukocyte integrins
- 15. crystallized fragment of an antibody
- 16. reaction which occurs within an organism for the purpose of defending against foreign invaders
- 17. highly pro-inflammatory cytokine produced by macrophages and T cells
- 19. a molecule that stimulates an immune response by activating leukocytes that fight disease
- 20. a lymphocyte subtype that develops and matures in the bone marrow
- 23. the end stage of disease in a HIV infection
- 27. genes
Down
- 2. repeating molecular patterns on microbes that are recognized by PRRs on immune cells
- 4. a subtype of a thymus-derived lymphocyte that expresses the co-receptor protein CD4
- 5. part of an innate immune response that kills infected cells kills by apoptosis
- 6. general designation of many of the different cytokines
- 7. subpopulation of T cells that suppress immune responses
- 8. a cytokine that is critical for immunity against viral infections and is commonly known as type II interferon
- 10. a virus that attacks the body's immune system and if not treated can lead to AIDS
- 12. leukocytes with multi-lobed nuclei and cytoplasmic granules
- 14. an immunoglobulin expressed on B cell surfaces
- 17. involved in stimulating B cells to produce antibody against extracellular pathogens
- 18. Y-shaped protein used by the immune system to identify and neutralize foreign objects
- 21. an immune response that does not involve antibodies but rather involves antigen presenting cells and T-cell lymphocytes
- 22. a cell wall component of gram negative bacteria
- 24. an immune cell that links the innate and adaptive arms of the immune system
- 25. a medication regimen used to manage and treat human immunodeficiency virus
- 26. receptors on immune cells and epithelial cells that recognize and bind to PAMPs on microbes
- 28. short DNA sequences that serve as the binding sites and allow for somatic recombination
- 29. transcription factor that helps activate the expression of many