Across
- 6. B-cell developmental signals involving growth factors
- 8. Enzyme that binds to RSS
- 10. First name of Nobel Prize winner in 1987 for discovery of the genetic principal for generation of antibody diversity
- 16. Present in all tissues. They engulf and kill microbes
- 17. Development of blood cell types
- 19. Type of cell that secretes histamine
- 23. Circulatory organ of lymphatic system
- 24. circulates blood and differentiates into macrophages
- 27. Intestinal cell type that produces antimicrobal peptides
- 28. Histone modifications are necessary to ensure _______ exclusion
- 30. A self-reactive lymphocyte will undergo____ selection
Down
- 1. Expression of a functional B cell receptor is a type of _________ regulation
- 2. immunity dependent on personal history
- 3. Region responsible for antibody function
- 4. Complete set of unique antigen receptors in an individual
- 5. Cell types include B cells, T cells, and NK cells
- 7. this type of cell division results in a stem cell and a functional specialization cell
- 9. this type of vessel drains into the lymph nodes
- 11. This kind of Stem Cell creates Lymphoid Stem Cell
- 12. death of cells
- 13. region that binds to an antigen
- 14. Location of T-cell development
- 15. ______ region that heavy chain defines and defines function of the antibody
- 18. Target of adaptive immune responses
- 20. bone marrow is where b-cell and NK cells ____
- 21. B and T cells reside in _____ nodes
- 22. Recognizes native antigen
- 25. Recognizes short peptide fragments
- 26. Disease resulting from the loss of all lymphocytes
- 29. Immunity that is genetically encoded in stem cells