Across
- 1. antibiotic that causes mRNA codon to be misread
- 3. S.aureus strain that is vancomycin-resistant and characterised by its thick cell wall and fewer peptidoglycan cross-links
- 5. group of human coronaviruses that SARS-CoV2 belongs to
- 8. when a bacterial population is susceptible to an antibiotic but isn't killed over the treatment duration
- 13. crucial target for antifungals
- 15. abbreviation; compound that when added to LPS lowers its charge and prevents colistin interaction
- 16. antibiotics that interfere with mRNA binding to ribosome
- 17. broad-spectrum antibiotics that cannot be used against Acinetobacter, Pseudomonas or enterobacteria but is highly effective against mycobacterial infections
- 18. gene that prevents vancomycin from binding by altering antibiotic binding target
- 19. antibiotic that blocks polypeptide exit tunnel and prevents peptide elongation
- 21. last-line treatment option for A.baumanii infections; type of polymyxin
Down
- 2. antibiotic that binds to 50S + inhibits peptide bond formation
- 4. antibiotics that prevent bacterial growth
- 6. antibiotic for M.tuberculosis which likely works by inhibiting arabinogalactan formation
- 7. abbreviation; bacteria that are non-susceptible to at least 1 agent in all but 2 or less antimicrobial categories
- 9. antibiotic that interacts with LPS and causes bacterial cell death
- 10. antibiotics that kill bacteria
- 11. when the level of activity is more than the addition of the 2 separate activities
- 12. gene that encodes modified PBP which has low affinity for beta-lactams in MRSA
- 14. anti-IL6 receptor antagonist typically used for severe rheumatoid arthritis but repurposed for COVID-19
- 20. amoxicillin is often combined with XXX acid to improve antimicrobial response